When, as a medical student in the 1950s, Kandel said he wanted to locate the ego and id in the brain, his mentor told him he was overreaching,... read more

When, as a medical student in the 1950s, Kandel said he wanted to locate the ego and id in the brain, his mentor told him he was overreaching, that the brain had to be studied "cell by cell." After his initial dismay, Kandel took on the challenge and in 2000 was awarded a Nobel Prize for his groundbreaking research showing how memory is encoded in the brain's neuronal circuits. Kandel's journey into the brain spans five decades, beginning in the era of early research into the role of electrical currents flowing through neurons and ending in the age of genetic engineering. It took him from early studies of reflexes in the lowly squid to the founding of a bioengineering firm whose work could some day develop treatments for Alzheimer's and on to a rudimentary understanding of the cellular mechanisms underlying mental illness. Kandel's life also took him on another journey: from Vienna, which his Jewish family fled after the Anschluss, to New York City and, decades later, on visits back to Vienna, where he boldly confronted Austria's unwillingness to look at its collusion in the Final Solution. For anyone considering a career in science, the early part of this intellectual autobiography presents a fascinating portrait of a scientist's formation: learning to trust his instincts on what research to pursue and how to pose a researchable question and formulate an experiment. Much of the science discussion is too dense for the average reader. But for anyone interested in the relationship between the mind and the brain, this is an important account of a creative and highly fruitful career. 50 b&w illus. (Mar.)
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Given the opportunity to watch the inner workings of his own brain, Steven Johnson jumps at the chance. He reveals the results in Mind Wide Open, an engaging... read more

Given the opportunity to watch the inner workings of his own brain, Steven Johnson jumps at the chance. He reveals the results in Mind Wide Open, an engaging and personal account of his foray into edgy brain science. In the 21st century, Johnson observes, we have become used to ideas such as "adrenaline rushes" and "serotonin levels," without really recognizing that complex neurobiology has become a commonplace thing to talk about. He sees recent laboratory revelations about the brain as crucial for understanding ourselves and our psyches in new, post-Freudian ways. Readers shy about slapping electrodes on their own temples can get a vicarious scientific thrill as Johnson tries out empathy tests, neurofeedback, and fMRI scans. The results paint a distinct picture of the author, and uncover general brain secrets at the same time. Memory, fear, love, alertness--all the multitude of states housed in our brains are shown to be the results of chemical and electrical interactions constantly fed and changed by input from our senses. Mind Wide Open both satisfies curiosity and provokes more questions, leaving readers wondering about their own gray matter. --Therese Littleton (hide)

Widely praised for its student-friendly style and exceptional artwork and pedagogy, Neuroscience: Exploring the Brain is a leading undergraduate textbook on the biology of the brain and the... read more

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Jeff Hawkins, the high-tech success story behind PalmPilots and the Redwood Neuroscience Institute, does a lot of thinking about thinking. In On Intelligence Hawkins juxtaposes his two loves--computers... read more

Jeff Hawkins, the high-tech success story behind PalmPilots and the Redwood Neuroscience Institute, does a lot of thinking about thinking. In On Intelligence Hawkins juxtaposes his two loves--computers and brains--to examine the real future of artificial intelligence. In doing so, he unites two fields of study that have been moving uneasily toward one another for at least two decades. Most people think that computers are getting smarter, and that maybe someday, they'll be as smart as we humans are. But Hawkins explains why the way we build computers today won't take us down that path. He shows, using nicely accessible examples, that our brains are memory-driven systems that use our five senses and our perception of time, space, and consciousness in a way that's totally unlike the relatively simple structures of even the most complex computer chip. Readers who gobbled up Ray Kurzweil's (The Age of Spiritual Machines and Steven Johnson's Mind Wide Open will find more intriguing food for thought here. Hawkins does a good job of outlining current brain research for a general audience, and his enthusiasm for brains is surprisingly contagious. --Therese Littleton (hide)